Ophthalmic pharmaceutical clinical trials: design considerations. (May 2015)

• Record Type: Journal Article
• Authors: Varner, Paul
• Is Part Of: Clinical investigation. Volume 5:Number 5(2015)
• Page Start: 457
• Page End: 475
• Publication Date: 2015-05
• Subjects: clinical trial -- ophthalmic -- trial assumptions -- trial design; Drugs -- Testing -- Periodicals; Drug development -- Periodicals; Clinical trials -- Periodicals; 615.580724
• DOI: 10.4155/cli.15.5
• Languages: English
• ISSNs: 2041-6806

Abstract

Evidence-based medicine requires diligent literature review in order to assess the findings of published clinical reports. Sound experimental procedures, based on the Scientific Method are conducted with a consideration of several background factors underlying clinical trial research. A discussion of these underpinnings and other factors influencing clinical trial design as they apply to ophthalmic pharmaceutical trials is provided, with the intent of providing a means of applying these considerations to literature review.