Cover Feature: Infrared Laser Desorption and Electrospray Ionisation of Non‐Covalent Protein Complexes: Generation of Intact, Multiply Charged Species (Analysis & Sensing 1/2021). Issue 1 (22nd December 2020)

• Record Type: Journal Article
• Authors: Kooijman, Pieter C.; Mathew, Anjusha; Ellis, Shane R.; Heeren, Ron M. A.
• Is Part Of: Analysis & Sensing. Volume 1:Issue 1(2021)
• Page Start: 2
• Page End: 2
• Publication Date: 2020-12-22
• Subjects: Electrospray ionisation -- laser desorption -- mass spectrometry -- non-covalent complexes -- proteins; Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; 543
• DOI: 10.1002/anse.202000037
• Languages: English
• ISSNs: 2629-2742

Abstract

Abstract : The Cover Feature shows a single laser ablation electrospray ionisation event for mass spectrometric analysis of protein complexes. The infrared laser ejects intact protein complexes containing droplets from a sample surface, to interact with an orthogonal nebula of charged electrospray droplets. These charges are transferred to the protein complexes at atmospheric pressure before entering the mass spectrometer inlet for analysis. More information can be found in the Communication by R. M. A. Heeren and co‐workers .