A Prospective Study in the Evaluation of Quality of Life After Vulvar Cancer Surgery. Issue 1 (1st January 2015)

• Record Type: Journal Article
• Authors: Novackova, Marta; Halaska, Michael J.; Robova, Helena; Mala, Ivana; Pluta, Marek; Chmel, Roman; Rob, Lukas
• Is Part Of: International journal of gynecological cancer. Volume 25:Issue 1(2015:Jan.)
• Page Start: 166
• Page End: 173
• Publication Date: 2015-01-01
• Subjects: Vulvar cancer -- Quality of life -- Questionnaire EORTC -- QLQ-C30 -- QLQ-CX24; Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1097/IGC.0000000000000313
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Objective: The aim of this study was to prospectively monitor the patients' quality of life (QoL) after vulvar cancer surgery. Design: The design was prospective clinical study. Setting: The study was set in the Department of Obstetrics and Gynecology, 2nd Medical Faculty of the Charles University and University Hospital Motol, Prague, Czech Republic. Methods: A group of 36 patients underwent vulvar cancer surgery: 24 patients were subject to inguinofemoral lymphadenectomy (RAD) and 12 to sentinel lymph node biopsy. To evaluate QoL, the European Organisation for Research and Treatment of Cancer, QoL questionnaires (QLQ-C30 and QLQ-CX24) were administered to patients before and 6 and 12 months after surgery. Results: In patients with vulvar cancer after inguinofemoral lymphadenectomy, increased fatigue and impaired lymphedema were observed. In the group of patients after sentinel lymph node biopsy, none of the QoL variables worsened postoperatively. Comparing both groups 12 months after surgery, the RAD group had significantly worse outcomes in body image and cognitive functioning than the sentinel lymph node biopsy group. Patients in the RAD group, who received adjuvant radiotherapy (n = 13), had worse QoL in symptom experience ( P < 0.05) at 6 and 12 months after the surgery than patients without radiotherapy (n = 11). Conclusions: Less radical surgery showed objectively better QoL results.