Temporary Central Vision Blindness After Oseltamivir Administration in a 15-Year-Old Pediatric Male Positive for Influenza A. (December 2021)

• Record Type: Journal Article
• Authors: Carson, Laura; Price, John E.
• Is Part Of: Hospital pharmacy. Volume 56:Number 6(2021)
• Page Start: 678
• Page End: 680
• Publication Date: 2021-12
• Subjects: adverse drug reactions -- anti-infectives -- eye -- ear -- nose -- throat -- infectious diseases -- medication safety -- disease management; Hospital pharmacies -- Periodicals; Pharmacy Service, Hospital; Hospital pharmacies; Periodicals; Periodicals; 615.1
• DOI: 10.1177/0018578720942225
• Languages: English
• ISSNs: 0018-5787

Abstract

Objective: A 15-year-old pediatric male patient was influenza A positive and started on oseltamivir at an outpatient clinic.Method: The next morning the patient presented to the emergency department (ED) with a chief complaint of visual disturbances including decreased central vision. Prior to presenting to the ED the patient was evaluated by his optometrist and his eye exam tested 20/400 bilaterally. His previous year's eye exam was normal, 20/25 bilaterally.Results: In the ED, the patient had an MRI which showed a normal appearing optic nerve, chiasm, and optic tracts. The oseltamivir therapy was discontinued, and the patient followed up with an ophthalmologist outpatient.Conclusion: At a 10-week follow-up visit the patient had 90% recovery of his vision.