Microwave hyperthermia treatment increases heat shock proteins in human skeletal muscle. Issue 7 (15th January 2007)

• Record Type: Journal Article
• Authors: Ogura, Yuji; Naito, Hisashi; Tsurukawa, Toshihiro; Ichinoseki-Sekine, Noriko; Saga, Norio; Sugiura, Takao; Katamoto, Shizuo
• Is Part Of: British journal of sports medicine. Volume 41:Issue 7(2007)
• Page Start: 453
• Page End: 455
• Publication Date: 2007-01-15
• Subjects: HSP, heat shock protein -- MHT, microwave hyperthermia treatment -- MyHC, myosin heavy chain; Sports medicine -- Periodicals; 617.1027
• DOI: 10.1136/bjsm.2006.032938
• Languages: English
• ISSNs: 0306-3674

Abstract

Abstract : Objective: To test the hypothesis that microwave hyperthermia treatment (MHT) increases heat shock proteins (HSPs) in the human vastus lateralis muscle. Methods: Four untrained healthy male volunteers participated in this study. The lateral side of the thigh of one leg (heated leg) was heated with a microwave generator (2.5 GHz, 150 W) for 20 min. At 1 day after the MHT, a muscle sample was taken from the heated leg. A control sample was taken from the unheated leg on another day of the MHT. For both legs, HSP90, HSP72 and HSP27 levels were compared. Results: The HSP90, HSP72 and HSP27 levels in heated legs were significantly higher than those in control legs (p<0.05). Conclusions: Application of MHT can increase the levels of several HSPs in human skeletal muscle.