An Approximate Analytical Method for the Evaluation of the Concentrations and Current for Hybrid Enzyme Biosensor. (17th February 2013)

• Record Type: Journal Article
• Authors: Krishnaperumal, Indira; Lakshmanan, Rajendran
• Other Names: Anusiewicz I. Academic Editor.; Reis H. Academic Editor.; Saint-Martin H. Academic Editor.
• Is Part Of: ISRN physical chemistry. Volume 2013(2013)
• Publication Date: 2013-02-17
• Subjects: Chemistry, Physical and theoretical -- Periodicals; Chemistry, Physical and theoretical; 35.10 physical chemistry: general; Periodicals; Electronic journals; 541
• DOI: 10.1155/2013/202781
• Languages: English
• ISSNs: 2090-7761

Abstract

Abstract : Mathematical modeling of amperometric biosensor with cyclic reaction is discussed. Analytical expressions pertaining to the concentration of substrate, cosubstrate, reducing agent and medial product and current for hybrid enzyme biosensor are obtained in terms of Thiele module and saturation parameters. In this paper, a powerful analytical method, called homotopy analysis method (HAM) is used to solve the system of nonlinear differential equations. Furthermore, in this work the numerical simulation of the problem is also reported using Scilab/Matlab program. Our analytical results are compared with simulation results. A good agreement between analytical and numerical results is noted.