Challenges in Enzymatic Route of Mannitol Production. (26th December 2012)

• Record Type: Journal Article
• Authors: Bhatt, Sheelendra Mangal; Mohan, Anand; Srivastava, Suresh Kumar
• Other Names: Betancor L. Academic Editor.; Garcia H. S. Academic Editor.; Jia J. Academic Editor.
• Is Part Of: ISRN biotechnology. Volume 2013(2013)
• Publication Date: 2012-12-26
• Subjects: Biotechnology -- Periodicals; Biotechnology; Biotechnology; Electronic journals; 660.6
• DOI: 10.5402/2013/914187
• Languages: English
• ISSNs: 2090-9403

Abstract

Abstract : Mannitol is an important biochemical often used as medicine and in food sector, yet its biotechnological is not preffered in Industry for large scale production, which may be due to the multistep mechanism involved in hydrogenation and reduction. This paper is a comparative preview covering present chemical and biotechnological approaches existing today for mannitol production at industrial scale. Biotechnological routes are suitable for adaptation at industrial level for mannitol production, and whatever concerns are there had been discussed in detail, namely, raw materials, broad range of enzymes with high activity at elevated temperature suitable for use in reactor, cofactor limitation, reduced by-product formation, end product inhibition, and reduced utilization of mannitol for enhancing the yield with maximum volumetric productivity.