Pulmonary and Peritoneal Tuberculosis Associated with Tumor Necrosis Factor-Alpha Inhibitor Use: A Case Report and Review of the Literature. (4th December 2012)

• Record Type: Journal Article
• Authors: Tipirneni, Niharika; Siegel, Marc O.
• Other Names: Borderías L. Academic Editor.; Bordon J. Academic Editor.
• Is Part Of: Case reports in pulmonology. Volume 2012(2012)
• Publication Date: 2012-12-04
• Subjects: Lungs -- Diseases -- Periodicals; Respiratory organs -- Diseases -- Periodicals; Respiratory infections -- Periodicals; Lung Diseases; Respiratory Tract Diseases; Respiratory Tract Infections; Lungs -- Diseases; Respiratory infections; Respiratory organs -- Diseases; Periodicals; Case Reports; Electronic journals; Periodicals; 616.2
• DOI: 10.1155/2012/598634
• Languages: English
• ISSNs: 2090-6846

Abstract

Abstract : The association between the use of tumor necrosis factor- α inhibitors and the increased risk of granulomatous infections, especially tuberculosis, has been well documented. Given the rapidly expanding list of inflammatory conditions for which tumor necrosis factor- α inhibitors are receiving FDA approval, the incidence of tuberculosis in this patient population has increased. Despite heightened awareness by physicians, the diagnosis of tuberculosis can remain challenging, given that extrapulmonary sites of infection are more frequently involved. We present a case of pulmonary and peritoneal tuberculosis in a gentleman being treated with a tumor necrosis factor- α inhibitor and discuss the diagnostic challenges of establishing the diagnosis.