Severe Primary HSV-2 in a Perinatal HIV-Infected Woman with Advanced Immunosuppression. (1st August 2012)

• Record Type: Journal Article
• Authors: Lee, Lana; Agwu, Allison; Hutton, Nancy
• Other Names: Husstedt Ingo W. Academic Editor.
• Is Part Of: Case reports in medicine. Volume 2012(2012)
• Publication Date: 2012-08-01
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Case Reports; Periodicals; 610
• DOI: 10.1155/2012/346039
• Languages: English
• ISSNs: 1687-9627

Abstract

Abstract : Herpes simplex virus type 2 (HSV-2) is most commonly associated with mucocutaneous manifestations; however, coinfections with HIV may be associated with atypical and more severe presentations of clinical disease. We present a case of a young woman with advanced perinatally acquired AIDS presenting with severe purulent pharyngitis, fevers, and toxic appearance with a subsequent diagnosis of disseminated primary HSV-2 infection in multiple noncontiguous mucocutaneous sites. This case highlights an unusual presentation of the protean nature of primary HSV infection and the potential severity of illness in patients with advanced immunosuppression.