Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases. (13th November 2012)

• Record Type: Journal Article
• Authors: Melikyan, G.; Abdelrahman, M. H.; D'Suoza, A.; Akhtar, N.; Elzouki, A. N.; Hammoudeh, M.
• Other Names: Aminov R. Academic Editor.; Mikdashi J. Academic Editor.; Njobvu P. Academic Editor.; Tso T. K. Academic Editor.
• Is Part Of: Case reports in rheumatology. Volume 2012(2012)
• Publication Date: 2012-11-13
• Subjects: Rheumatology -- Periodicals; Rheumatology -- Case studies -- Periodicals; Rheumatic Diseases; Connective Tissue Diseases; Rheumatology; Periodicals; Electronic journals; Case studies; Periodicals; 616.723
• DOI: 10.1155/2012/515768
• Languages: English
• ISSNs: 2090-6889

Abstract

Abstract : Transverse myelitis (TM) is an inflammatory process involving a restricted area of the spinal cord. The usual dramatic presentation makes TM a medical emergency. Early detection and aggressive therapy are required in order to improve the prognosis. The association of this unique clinical phenotype and autoantibody provides circumstantial evidence that an autoimmune aetiology might be involved. We describe two cases of TM associated with anti-Ro (SSA) autoantibodies without connective tissue disease manifestations. The two patients were treated successfully with IV steroids and cyclophosphamide.