A Metastasizing Squamous Cell Carcinoma Arising in a Solitary Epidermal Nevus. (1st August 2012)

• Record Type: Journal Article
• Authors: Toya, Masami; Endo, Yuichiro; Fujisawa, Akihiro; Tanioka, Miki; Yoshikawa, Yoshiaki; Tachibana, Takao; Miyachi, Yoshiki
• Other Names: Curzio M. Academic Editor.; Lee J.-H. Academic Editor.; Salopek T. Academic Editor.
• Is Part Of: Case reports in dermatological medicine. Volume 2012(2012)
• Publication Date: 2012-08-01
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; 616.5005
• DOI: 10.1155/2012/109632
• Languages: English
• ISSNs: 2090-6463

Abstract

Abstract : Aim . Secondary tumor rarely develops from epidermal nevus. We present a case of a metastasizing squamous cell carcinoma that developed in a solitary epidermal nevus. Case Report . An 82-years old Japanese female was presented with a red tumor on the left axilla. She reported that the tumor developed in a congenital epidermal nevus. A biopsy of the tumor showed that a well-differentiated squamous cell carcinoma (SCC) arose from the epidermal nevus. As a lymph node metastasis was found by sentinel lymph node biopsy, the patient received surgical excision of the lesion, axillary lymph node dissection, and postoperative radiation. Discussion . Secondary tumors developing in epidermal nevus are rare. To the best of our knowledge, only in two cases including the present case, SCC developed in a solitary epidermal nevus. There is no established clinical guideline for prophylactic removal of epidermal nevus. However, a biopsy should be done if a secondary malignancy is suspected in an epidermal nevus.