Brazilian Green Propolis Compared to Miconazole Gel in the Treatment of Candida-Associated Denture Stomatitis. (2nd May 2013)

• Record Type: Journal Article
• Authors: Capistrano, Hermínia Marques; de Assis, Eliene Magda; Leal, Rosana Maria; Alvarez-Leite, Maria Eugênia; Brener, Sylvie; Bastos, Esther Margarida Alves Ferreira
• Other Names: Czuba Zenon Academic Editor.
• Is Part Of: Evidence-based complementary and alternative medicine. Volume 2013(2013)
• Publication Date: 2013-05-02
• Subjects: Alternative medicine -- Periodicals; 615.505
• DOI: 10.1155/2013/947980
• Languages: English
• ISSNs: 1741-427X

Abstract

Abstract : Aim . To evaluate the efficacy of Brazilian green propolis in comparison to miconazole gel in the treatment of Candida -associated denture stomatitis. Methods . Forty-five denture stomatitis patients, with palatal mucosa erythema levels classified according to Newtons's criteria and with positive culture to Candida spp., were randomly divided into three treatment groups: 15 received miconazole gel 2%, 15 received propolis gel 2, 5%, and 15 received propolis 24% for mouthwash. After four daily use lasting two weeks, they were reexamined for the denture stomatitis degree and for a second culture of Candida . The Wilcoxon's test was applied to compare the results of clinical classification of the denture stomatitis and the Candida spp. colonies numbers, before and after each treatment. The Kruskall-Wallis's test was used to compare efficacy among the three treatment groups. Results . There were a significant reduction or complete remission of denture stomatitis ( P < 0.05 ) and a significant decrease of Candida colonies for the three groups ( P < 0.05 ). There was no difference in the efficacy among the treatment groups ( P > 0.05 ) . Conclusion . Brazilian green propolis has a similar effect as miconazole in the treatment of Candida -associated denture stomatitis being an alternative in the therapeutics of this condition.