Correlation between Density and Resorption of Fresh-Frozen and Autogenous Bone Grafts. (24th June 2014)

• Record Type: Journal Article
• Authors: Lumetti, Simone; Galli, Carlo; Manfredi, Edoardo; Consolo, Ugo; Marchetti, Claudio; Ghiacci, Giulia; Toffoli, Andrea; Bonanini, Mauro; Salgarelli, Attilio; Macaluso, Guido M.
• Other Names: Gasparini Giulio Academic Editor.
• Is Part Of: BioMed research international. Volume 2014(2014)
• Publication Date: 2014-06-24
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2014/508328
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Trial Design . This analysis compared the outcome of fresh-frozen versus autologous bone block grafts for horizontal ridge augmentation in patients with Cawood and Howell class IV atrophies. Methods . Seventeen patients received autologous grafts and 21 patients received fresh-frozen bone grafts. Patients underwent CT scans 1 week and 6 months after surgery for graft volume and density analysis. Results . Two autologous and 3 fresh-frozen grafts failed. Autologous and fresh-frozen grafts lost, respectively, 28% and 46% of their initial volume ( P = 0.028 ) . It is noteworthy that less dense fresh-frozen blocks lost more volume than denser grafts (61% versus 16%). Conclusions . According to these 6-month results, only denser fresh-frozen bone graft may be an acceptable alternative to autologous bone for horizontal ridge augmentation. Further studies are needed to investigate its behaviour at longer time points.