Gastrointestinal Histoplasmosis Mimicking Crohn's Disease. (16th May 2021)

• Record Type: Journal Article
• Authors: Shojaei, Esfandiar; Walsh, Joanna C; Sangle, Nikhil; Yan, Brian; Silverman, Michael S; Hosseini-Moghaddam, Seyed M
• Is Part Of: Open forum infectious diseases. Volume 8:Number 7(2021)
• Publication Date: 2021-05-16
• Subjects: alcoholism -- gastrointestinal histoplasmosis -- inflammatory bowel disease; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofab249
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: Disseminated histoplasmosis is a life-threatening disease usually seen in immunocompromised patients living in endemic areas. We present an apparently immunocompetent patient with gastrointestinal histoplasmosis who was initially diagnosed with biopsy-proven Crohn's disease. Following discontinuation of anti-inflammatory drugs and institution of antifungal therapy, his gastrointestinal illness completely improved. Specific fungal staining should be routinely included in histopathologic assessment of tissue specimens diagnosed as Crohn's disease.