Recurrent solitary fibrous tumor of the pleura with malignant transformation: a case report. Issue 7 (6th July 2021)

• Record Type: Journal Article
• Authors: Sakamoto, Risa; Hamahiro, Tomoka; Maeda, Ryo; Ayabe, Takanori; Tomita, Masaki; Tanaka, Hiroyuki
• Is Part Of: Journal of surgical case reports. Volume 2021:Issue 7(2021)
• Publication Date: 2021-07-06
• Subjects: Surgery -- Periodicals; Surgery -- Case studies -- Periodicals; 617.005
• DOI: 10.1093/jscr/rjab283
• Languages: English
• ISSNs: 2042-8812

Abstract

Abstract: We report a rare case of recurrent solitary fibrous tumor (SFT) of the pleura with suspicious malignant transformation. A 78-year-old man had undergone prior surgical resection of the primary and recurrent SFT tumors at 11 and 2 years before the current presentation. Although his primary tumor had a round shape and did not show invasive growth, the current recurrent tumor extended through the neural foramen and had an osteoclastic progression into the thoracic spine. A computed tomography (CT) guided needle biopsy was performed and the pathological diagnosis of the tumor was confirmed as the recurrence of SFT. Immunohistochemically, the MIB-1 proliferation index (Ki-67) of the primary tumor and the current tumor was 1.74 and 30.00%, respectively. These clinical and immunohistochemical findings were strongly suspected the malignant transformation of SFT from benign. He was treated with radiotherapy, and a response was observed.