Impact of restricting procalcitonin measurements in a Swiss tertiary-care hospital on antibiotic use, clinical outcomes, and costs: An interrupted time-series analysis. (2nd July 2021)

• Record Type: Journal Article
• Authors: Abbas, Mohamed; Vernaz, Nathalie; von Dach, Elodie; Vuilleumier, Nicolas; Harbarth, Stephan J.; Huttner, Benedikt D.
• Is Part Of: Infection control and hospital epidemiology. Volume 42:Number 7(2021)
• Page Start: 890
• Page End: 892
• Publication Date: 2021-07-02
• Subjects: Nosocomial infections -- Epidemiology -- Periodicals; Health facilities -- Sanitation -- Periodicals; Hospital buildings -- Sanitation -- Periodicals; Cross Infection -- Periodicals; Epidemiology -- Periodicals; Hospitals -- Periodicals; Infection Control -- Periodicals; 614.44
• DOI: 10.1017/ice.2020.1314
• Languages: English
• ISSNs: 0899-823X

Abstract

Abstract: We evaluated the impact of a restriction of procalcitonin measurements on antibiotic use, length of stay, mortality, and cost in a Swiss tertiary-care hospital using interrupted time-series analysis. There was no significant change in level or slope for rates of antibiotic consumption, and costs decreased considerably, by ~54, 488 CHF (US$55, 714) per month.