A Photoinduced Multicomponent Regioselective Synthesis of 1, 4, 5‐Trisubstituted‐1, 2, 3‐Triazoles: Transition Metal‐, Azide‐ and Oxidant‐Free Protocol. Issue 14 (24th June 2021)

• Record Type: Journal Article
• Authors: Sai Allaka, Bhargava; Basavoju, Srinivas; Rama Krishna, Gamidi
• Is Part Of: Advanced synthesis & catalysis. Volume 363:Issue 14(2021)
• Page Start: 3560
• Page End: 3565
• Publication Date: 2021-06-24
• Subjects: 1, 4, 5-trisubstituted-1, 2, 3-triazoles -- transition metal-, azide- and oxidant free protocol -- multicomponent reaction -- cycloaddition -- molecular diversity -- regioselectivity -- milder reaction conditions; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202100321
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A transition metal‐ and azide‐free approach is explored to synthesize 1, 4, 5‐trisubstituted‐1, 2, 3‐triazoles under sunlight. The reaction proceeds via C−N and N−N bond formations. These regioselective 1, 2, 3‐triazoles are obtained from isatin Schiff bases, benzaldehydes and tosylhydrazine in the presence of base. This protocol offers the structurally diverse 1, 2, 3‐triazole derivatives with 75–90% yields. Abstract :