Access to α, β-unsaturated carboxylic acids through water-soluble palladium catalyzed hydroxycarbonylation of alkynes using water as the solvent. Issue 14 (30th June 2021)

• Record Type: Journal Article
• Authors: Lv, Jinhe; Zong, Lingbo; Zhang, Jinrong; Song, Jiaxin; Zhao, Jinyu; Zhang, Kai; Zhou, Ziqin; Gao, Mingjie; Xie, Congxia; Jia, Xiaofei; Ren, Xinyi
• Is Part Of: Catalysis science & technology. Volume 11:Issue 14(2021)
• Page Start: 4708
• Page End: 4713
• Publication Date: 2021-06-30
• Subjects: Catalysis -- Periodicals; 541.395
• DOI: 10.1039/d1cy00699a
• Languages: English
• ISSNs: 2044-4753

Abstract

Abstract : A reusable water-soluble Pd(OAc)2 /sulfoxantphos catalyst has been developed for the hydroxycarbonylation of symmetrical and unsymmetrical alkynes with CO/H2 O to afford the corresponding α, β-unsaturated carboxylic acids in good yields. Abstract : A sulfoxantphos modified palladium-catalyzed synthesis of α, β-unsaturated carboxylic acids from alkynes with CO and H2 O was described. The atom-economic hydroxycarbonylation of various symmetrical and unsymmetrical alkynes can be achieved with chemo-, stereo-, and regioselectivity, affording the corresponding carboxylic acids in good to excellent yields. Using water as the reaction solvent, the water-soluble palladium catalyst was easily separated from the product and could be reused for 5 cycles.