Current challenges in identification of clinical characteristics and detection of COVID-19: A comprehensive review. (August 2021)

• Record Type: Journal Article
• Authors: More, Namdev; Ranglani, Deepak; Kharche, Shubham; Choppadandi, Mounika; Ghosh, Sumanta; Vaidya, Sumedh; Kapusetti, Govinda
• Is Part Of: Measurement. Volume 16(2021)
• Publication Date: 2021-08
• Subjects: Coronavirus -- Characteristics of COVID-19 -- Diagnostic methods of COVID-19 -- RT-PCR -- Point of care device; Detectors -- Periodicals; Measurement -- Periodicals; 530.7
• DOI: 10.1016/j.measen.2021.100052
• Languages: English
• ISSNs: 2665-9174

Abstract

Abstract: World Health Organization (WHO) declares the COVID-19 outbreak as a pandemic. The newly emerging infection has caused around one million deaths worldwide and still counting. There is no specific treatment for the disease, and it can only contain by breaking the spread. So that early and rapid diagnosis of the infection is the only way to control the outbreak. The COVID-19 virus affects the human respiratory system and subsequently infects other vital organs. In consideration of the diagnosis, the present review focuses on the critical diagnostic approaches for COVID-19, including RT-PCR, Chest-CT scan, some biosensor-based systems, etc. Moreover, this review is a specific bird's eye view on recent developments on the point of care devices and related technologies. Additionally, it presented a small glimpse of the pathophysiology and structural aspects of COVID-19. Therefore, the current review can motivate and help the reader to develop cutting-edge diagnostic technologies for the early and rapid detection of the COVID-19. Graphical abstract: Image 1 Highlights: Summarize the available data on diagnosis tools of COVID 19 and their potential limitations Discuss the pathophysiology of COVID-19 in human Emphasis on rapid testing of COVID 19 to contain the disease Disuses in details about various diagnosis methods of COVID 19 Suggested some potential alternatives for development of rapid and specific sensors/kits for COVID-19