Architected implant designs for long bones: Advantages of minimal surface-based topologies. (September 2021)

• Record Type: Journal Article
• Authors: Hsieh, Meng-Ting; Begley, Matthew R.; Valdevit, Lorenzo
• Is Part Of: Materials & design. Volume 207(2021)
• Publication Date: 2021-09
• Subjects: Bone implants -- Architected materials -- Triply periodic minimal surfaces -- Spinodal shell -- Finite element analysis; Materials -- Periodicals; Engineering design -- Periodicals; Matériaux -- Périodiques; Conception technique -- Périodiques; Electronic journals; 620.11
• DOI: 10.1016/j.matdes.2021.109838
• Languages: English
• ISSNs: 0264-1275

Abstract

Graphical abstract: Highlights: Beam- and surface-based lattice topologies are all suitable for bone implant design. In surface-based topologies, specific area and implant stiffness can be decoupled. Surface-based topologies are more efficient at promoting bone growth than beam-based topologies. Stochastic spinodal shell topologies require the smallest safety factor. Abstract: Large bone fractures often require porous implants for complete healing. In this work, we numerically investigate the suitability of three topologically very different architected materials for long bone implants: the octet truss-based lattice, the Schwartz P minimal surface-based lattice and the spinodal stochastic surface-based lattice. Each implant topology (reinforcement) and its surrounding tissue (soft matrix) are modeled as a composite system via finite element analysis. Performance metrics are defined based on the Young's modulus, the peak stress under service conditions, the interfacial surface area per unit volume and the relative bone growth rate (estimated based on the strain transferred to the soft matrix). We show that surface-based topologies are less prone to fatigue failure and may promote superior bone growth than conventional truss-based designs. Spinodal surface-based architected materials have the best performance, and can be fabricated via self-assembly approaches followed by material conversion, potentially allowing scalable fabrication of implants with unit cell sizes at the micro-scale, thus dramatically amplifying surface area per unit volume and bone growth efficiency.