Rhabdomyolysis following Acute Extended-Release Quetiapine Poisoning: A Case Report. (13th December 2012)

• Record Type: Journal Article
• Authors: Liolios, Antonios; Sentissi, Othman
• Other Names: Dell'Osso L. Academic Editor.; Jönsson E. Academic Editor.; Matsuzawa D. Academic Editor.
• Is Part Of: Case reports in psychiatry. Volume 2012(2012)
• Publication Date: 2012-12-13
• Subjects: Psychiatry -- Periodicals; Psychiatry -- Case studies -- Periodicals; Mental Disorders; Psychiatry; Psychiatry; Periodicals; Case studies; Periodicals; 616.89
• DOI: 10.1155/2012/347421
• Languages: English
• ISSNs: 2090-682X

Abstract

Abstract : Background . During the past few years, there have been a number of case reports concerning rhabdomyolysis following quetiapine poisoning; however, there has been none concerning the medication in its extended-release form. Methods . We present the case report of a 48-year-old man presenting a major depressive disorder and borderline personality disorder, who after voluntary intoxication with 12000 mg of quetiapine extended-release developed signs of acute rhabdomyolysis. Results . The rhabdomyolysis was confirmed by the laboratory and the clinical findings, with elevated levels of creatinine, creatine phosphokinase, and CRP. Discussion . We would like to pinpoint the importance of this complication and our concern of prescribing it for psychiatric patients with chronic somatic comorbidities.