Leiomyosarcoma of Pulmonary Vein Presenting as Left Atrial Mass: An Outline of Management Principles. (6th November 2012)

• Record Type: Journal Article
• Authors: Gukop, Philemon; Frassetto, Guido; Karapanagiotidis, Georgios; Chandrasekaran, Venkatachalam
• Other Names: Chen M.-R. Academic Editor.; Jim M.-H. Academic Editor.
• Is Part Of: Case reports in cardiology. Volume 2012(2012)
• Publication Date: 2012-11-06
• Subjects: Cardiology -- Periodicals; 616.12005
• DOI: 10.1155/2012/396319
• Languages: English
• ISSNs: 2090-6404

Abstract

Abstract : Leiomyosarcoma of the pulmonary vein is rare and has poor prognosis. Its clinical features are nonspecific and mimic benign conditions. Early diagnosis is challenging. Most cases have been diagnosed only at autopsy or on postoperative histology specimens. Treatment is essentially palliative complete surgical excision. We outline the principles of management with the case of a 39-year-old man with leiomyosarcoma of the left pulmonary veins extending into the left atrium. Extensive investigation to achieve early diagnosis and determine extent of disease is essential. Frozen section guided adequate excision of all cardiac tumours and resection of involved lung tissue achieve local disease control. Adjuvant chemoradiotherapy has been shown to enhance survival.