Esophageal Sarcoidosis: A Review of Cases and an Update. (5th March 2013)

• Record Type: Journal Article
• Authors: Abraham, Albin; Hajar, Rabab; Virdi, Ravi; Singh, Jaspreet; Mustacchia, Paul
• Other Names: Karayiannakis A. J. Academic Editor.; Sperti C. Academic Editor.
• Is Part Of: ISRN gastroenterology. Volume 2013(2013)
• Publication Date: 2013-03-05
• Subjects: Gastroenterology -- Periodicals; Digestive organs -- Diseases -- Periodicals; Digestive organs -- Diseases; Gastroenterology; Gastroenterology; Gastrointestinal Diseases; Fulltext; Internet Resources; Periodicals; Electronic journals; Periodicals; Periodical; 616.3
• DOI: 10.1155/2013/836203
• Languages: English
• ISSNs: 2090-4398

Abstract

Abstract : Sarcoidosis is a chronic disorder that can virtually affect any organ system in the body. Histologically, it is characterized by the presence of T lymphocytes, mononuclear phagocytes, and noncaseating granulomas. Most commonly affected are the intrathoracic structures, with 90% of the reported cases involving the lungs. Esophageal involvement in sarcoidosis is extremely rare. Dysphagia is the most common presentation in these patients and can be attributed to various mechanisms such as direct esophageal wall infiltration, extrinsic compression, cranial neuropathy, and brainstem involvement. A thorough online literature review revealed only 23 reported cases of esophageal involvement in sarcoidosis. This paper reviews these reported cases in detail along with newer diagnostic and treatment options, including direction of future therapy.