Effect of Biometric Characteristics on the Change of Biomechanical Properties of the Human Cornea due to Cataract Surgery. (29th May 2014)

• Record Type: Journal Article
• Authors: Song, Xuefei; Langenbucher, Achim; Gatzioufas, Zisis; Seitz, Berthold; El-Husseiny, Moatasem
• Other Names: Sanchis-Gimeno Juan A. Academic Editor.
• Is Part Of: BioMed research international. Volume 2014(2014)
• Publication Date: 2014-05-29
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2014/628019
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Purpose. To determine the impact of biometric characteristics on changes of biomechanical properties of the human cornea due to standard cataract surgery using biomechanical analysis. Patients and Methods. This prospective consecutive cross-sectional study comprised 54 eyes with cataract in stages I or II that underwent phacoemulsification and IOL implantation. CH, CRF, IOPg, and IOPcc intraocular pressure were measured by biomechanical analysis preoperatively and at 1 month postoperatively. Changes (Δ ) were calculated as preoperative value versus postoperative value. Biometrical data were extracted from TMS-5 (CSI and SAI), IOLMaster (AL), and EM-3000 (CCT and ECC) preoperatively. Results. The average values of the changes were Δ CH = - 0.45 ± 1.27 mmHg, Δ CRF = - 0.88 ± 1.1 mmHg, Δ IOPg = - 1.58 ± 3.15 mmHg, and Δ IOPcc = - 1.45 ± 3.93 mmHg. The higher the CSI the smaller the decrease in CH (r = 0.302, P = 0.028 ). The higher the CCT the larger the decrease in CRF (r = - 0.371, P = 0.013 ). The higher the AL the smaller the decrease in IOPg (r = 0.417, P = 0.005 ). The higher the AL, SAI, and EEC the smaller the decrease in IOPcc (r = 0.351, P = 0.001 ; r = - 0.478, P < 0.001 ; r = 0.339, P = 0.013 ). Conclusions. Corneal biomechanical properties were affected by comprehensive factors after cataract surgery, including corneal endothelium properties, biometry, and geometrical characteristics.