Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case Report. (14th August 2012)

• Record Type: Journal Article
• Authors: Torres-Mora, Jorge; Moyer, Ann; Topazian, Mark; Alexander, Jeffrey; Wu, Tsung-Teh; Seys, Amber; Fritchie, Karen
• Other Names: Altintas E. Academic Editor.; Mourad F. H. Academic Editor.; Sugimura H. Academic Editor.
• Is Part Of: Case reports in gastrointestinal medicine. Volume 2012(2012)
• Publication Date: 2012-08-14
• Subjects: Gastroenterology -- Case studies -- Periodicals; Digestive organs -- Diseases -- Periodicals; Gastroenterology; Gastrointestinal Diseases; Digestive organs -- Diseases; Gastroenterology; Electronic journals; Periodicals; Case studies; Periodicals; 616.33
• DOI: 10.1155/2012/141693
• Languages: English
• ISSNs: 2090-6528

Abstract

Abstract : Liposarcoma is one of the most common sarcomas in adults, but only rarely presents as an esophageal primary. There have been several reports of well-differentiated liposarcoma (WDL) arising in the esophagus, but we present a case of dedifferentiated liposarcoma (DL) presenting as a large esophageal polyp. We believe this is the first reported case of DL of the esophagus with morphologic evidence of both well-differentiated and dedifferentiated components. The diagnosis was confirmed by demonstration of CPM gene amplification by fluorescence in situ hybridization (FISH).