Aromatic compounds from the sclerotia of Inonotus obliquus. Issue 14 (18th July 2021)

• Record Type: Journal Article
• Authors: Zou, Chun-xin; Zhang, Yang-Yang; Bai, Ming; Huang, Xiao-Xiao; Wang, Xiao-Bo; Song, Shao-Jiang
• Is Part Of: Natural product research. Volume 35:Issue 14(2021)
• Page Start: 2454
• Page End: 2457
• Publication Date: 2021-07-18
• Subjects: Inonotus obliquus -- aromatic compounds -- ECD calculation -- cytotoxicity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1677656
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Three new aromatic compounds (1a /1b, 2 ) including a pair of enantiomers (1a /1b ), were isolated from Inonotus obliquus . The structures of the new compounds were elucidated by extensive spectroscopic analyses, and the absolute configurations of 1a and 1b were determined by electronic circular dichroism (ECD) calculated. All isolates were evaluated for their cytotoxic activities against Hep3B and HepG2 cell lines. Compounds 1b and 2 showed weak cytotoxicity toward the Hep3B cells at 25 μM. Graphical Abstract: