A new polyketide from the bark of Hypericum roeperianum Schimp. (Hypericaceae). Issue 14 (29th June 2021)

• Record Type: Journal Article
• Authors: Damen, François; Demgne, Olive Monique F.; Bitchagno, Gabin Thierry M.; Celik, Ilhami; Mpetga, James D. Simo; Tankeo, Simplice Beaudelaire; Opatz, Till; Kuete, Victor; Tane, Pierre
• Is Part Of: Natural product research. Volume 35:Issue 14(2021)
• Page Start: 2381
• Page End: 2387
• Publication Date: 2021-06-29
• Subjects: Hypericum roeperianum -- Hypericaceae -- polyketide -- antibacterial -- MDR; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1677655
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: The isolation and spectroscopic data of a hitherto undescribed polyketide (1 ) from Hypericum roeperianum Schimp. (Hypericaceae) together with six known compounds (2 –7 ) is herein reported. The structure elucidation is based on extensive 1D- and 2D-NMR, infrared, UV and MS experiments. The structures of the known compounds were confirmed by comparison of their spectroscopic data with those of similar reported compounds in the literature. Some of the isolated compounds had a significant activity against a panel of multidrug-resistant bacterial strains. Supplemental data for this article can be accessed at https://doi.org/10.1080/14786419.2019.1677655 . Graphical Abstract: