Araçain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw. Issue 14 (18th July 2021)

• Record Type: Journal Article
• Authors: Macaúbas-Silva, Camila; Félix, Maysa D. G.; Aquino, Ana Karoline S. de; Pereira-Júnior, Paulo G.; Brito, Emmily Vieira de O.; Oliveira-Filho, Abrahão A. de; Igoli, John O.; Watson, David G.; Teles, Yanna C. F.
• Is Part Of: Natural product research. Volume 35:Issue 14(2021)
• Page Start: 2424
• Page End: 2428
• Publication Date: 2021-07-18
• Subjects: Psidium guineense Sw. -- araçain -- 2-(4-hydroxyphenyl)ethyl hexanoate -- Klebsiella pneumoniae; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1672683
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Psidium guineense Sw. (Myrtaceae) is a shrub distributed all over South America and Brazil. Its leaves are traditionally used to treat digestive problems and infections. Several biological activities have been reported for P. guineense extracts, however phytochemical studies are scarce. The present study is on the isolation of compounds from P. guineense leaf extracts using chromatographic and spectroscopic techniques and evaluation of their antibacterial activity. Araçain, a tyrosol derivative was isolated as a natural product for the first time. Other compounds isolated were ursolic acid, a phaeophorbide and three flavonoids. The extracts were tested for their antimicrobial activity against Klebsiella pneumoniae strains and they showed moderate to high antibacterial activity. Graphical Abstract: