Agomelatine Augmentation of Escitalopram Therapy in Treatment-Resistant Obsessive-Compulsive Disorder: A Case Report. (9th October 2012)

• Record Type: Journal Article
• Authors: De Berardis, Domenico; Serroni, Nicola; Marini, Stefano; Martinotti, Giovanni; Ferri, Francesca; Callista, Gaetano; La Rovere, Raffaella; Moschetta, Francesco Saverio; Di Giannantonio, Massimo
• Other Names: Jönsson E. Academic Editor.; Kluge M. Academic Editor.
• Is Part Of: Case reports in psychiatry. Volume 2012(2012)
• Publication Date: 2012-10-09
• Subjects: Psychiatry -- Periodicals; Psychiatry -- Case studies -- Periodicals; Mental Disorders; Psychiatry; Psychiatry; Periodicals; Case studies; Periodicals; 616.89
• DOI: 10.1155/2012/642752
• Languages: English
• ISSNs: 2090-682X

Abstract

Abstract : Obsessive-compulsive disorder (OCD) is a chronic condition characterized by obsessions or compulsions that cause distress or interfere with functioning. Selective serotonin reuptake inhibitors are the first-line strategy in the treatment of OCD, but approximately 40% to 60% of patients with OCD fail to respond to them. Several augmentation strategies have been proposed, including the use of atypical antipsychotics and antidepressant combinations. In the present paper we describe the case of a young female patient suffering from severe treatment-resistant OCD who remitted as a result of agomelatine augmentation of escitalopram therapy.