Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients. (15th August 2012)

• Record Type: Journal Article
• Authors: Vyas, Jatin M.; Marasco, Wayne A.
• Other Names: Gozlan J. Academic Editor.; Marangoni A. Academic Editor.; Walder G. Academic Editor.
• Is Part Of: Case reports in infectious diseases. Volume 2012(2012)
• Publication Date: 2012-08-15
• Subjects: Communicable diseases -- Periodicals; Communicable diseases -- Case studies -- Periodicals; Communicable Diseases; Infectious Disease Medicine; Communicable diseases; Electronic journals; Periodicals; Case studies; Periodicals; 616.9
• DOI: 10.1155/2012/463569
• Languages: English
• ISSNs: 2090-6625

Abstract

Abstract : We report two cases of fatal hepatic failure in patients who received matched unrelated bone marrow transplantation. Both patients presented with high fevers, abnormal liver functions tests, and hypodense lesions in the liver by CT scan. Histologic examination of postmortem liver samples demonstrated extensive necrosis, and immunohistochemistry was positive for adenovirus.