Host-Microbe Interactions in Caenorhabditis elegans. (31st July 2013)

• Record Type: Journal Article
• Authors: Zhang, Rui; Hou, Aixin
• Other Names: Hamood A. Academic Editor.; Navarro-Garcia F. Academic Editor.
• Is Part Of: ISRN microbiology. Volume 2013(2013)
• Publication Date: 2013-07-31
• Subjects: Microbiology -- Periodicals; Microbiology; Microbiological Phenomena; Fulltext; Internet Resources; Periodicals; 579
• DOI: 10.1155/2013/356451
• Languages: English
• ISSNs: 2090-7478

Abstract

Abstract : A good understanding of how microbes interact with hosts has a direct bearing on our capability of fighting infectious microbial pathogens and making good use of beneficial ones. Among the model organisms used to study reciprocal actions among microbes and hosts, C. elegans may be the most advantageous in the context of its unique attributes such as the short life cycle, easiness of laboratory maintenance, and the availability of different genetic mutants. This review summarizes the recent advances in understanding host-microbe interactions in C. elegans . Although these investigations have greatly enhanced our understanding of C. elegans -microbe relationships, all but one of them involve only one or few microbial species. We argue here that more research is needed for exploring the evolution and establishment of a complex microbial community in the worm's intestine and its interaction with the host.