Cover Feature: A "Multi‐Heavy‐Atom" Approach toward Biphotonic Photosensitizers with Improved Singlet‐Oxygen Generation Properties (Chem. Eur. J. 38/2019). Issue 38 (5th June 2019)

• Record Type: Journal Article
• Authors: Galland, Margaux; Le Bahers, Tangui; Banyasz, Akos; Lascoux, Noëlle; Duperray, Alain; Grichine, Alexei; Tripier, Raphaël; Guyot, Yannick; Maynadier, Marie; Nguyen, Christophe; Gary‐Bobo, Magali; Andraud, Chantal; Monnereau, Cyrille; Maury, Olivier
• Is Part Of: Chemistry. Volume 25:Issue 38(2019)
• Page Start: 8914
• Page End: 8914
• Publication Date: 2019-06-05
• Subjects: gadolinium -- intersystem crossing -- lanthanides -- photodynamic therapy -- two-photon microscopy; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201901890
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract : Towards improved lanthanide complexes for two‐photon mediated singlet oxygen production: The very large intersystem crossing efficiency results from the combination and interplay of bromine atom substituents, placed along the π‐conjugated antenna, and a heavy rare‐earth element coordinated to a central TACN ligand. Two‐photon‐activated singlet oxygen generation leads to tumor cell death, which illustrates the potential of this new class of compounds as theragnostic agents. More information can be found in the Full Paper by M. Gary‐Bobo, C. Andraud, C. Monnereau, O. Maury, et al. on page 9026 .