An international investigation into O red blood cell unit administration in hospitals: the GRoup O Utilization Patterns (GROUP) study. Issue 10 (25th August 2017)

• Record Type: Journal Article
• Authors: Zeller, Michelle P.; Barty, Rebecca; Aandahl, Astrid; Apelseth, Torunn O.; Callum, Jeannie; Dunbar, Nancy M.; Elahie, Allahna; Garritsen, Henk; Hancock, Helen; Kutner, José Mauro; Manukian, Belinda; Mizuta, Shuichi; Okuda, Makoto; Pagano, Monica B.; Pogłód, Ryszard; Rushford, Kylie; Selleng, Kathleen; Sørensen, Claess Henning; Sprogøe, Ulrik; Staves, Julie; Weiland, Thorsten; Wendel, Silvano; Wood, Erica M.; van de Watering, Leo; van Wordragen‐Vlaswinkel, Maria; Ziman, Alyssa; Jan Zwaginga, Jaap; Murphy, Michael F.; Heddle, Nancy M.; Yazer, Mark H.
• Is Part Of: Transfusion. Volume 57:Issue 10(2017)
• Page Start: 2329
• Page End: 2337
• Publication Date: 2017-08-25
• Subjects: Hematology -- Periodicals; Blood -- Transfusion -- Periodicals; Blood Group Antigens -- Periodicals; Blood Preservation -- Periodicals; Blood Transfusion -- Periodicals; 615
• DOI: 10.1111/trf.14255
• Languages: English
• ISSNs: 0041-1132

Abstract

Abstract : BACKGROUND: Transfusion of group O blood to non‐O recipients, or transfusion of D– blood to D+ recipients, can result in shortages of group O or D– blood, respectively. This study investigated RBC utilization patterns at hospitals around the world and explored the context and policies that guide ABO blood group and D type selection practices. STUDY DESIGN AND METHODS: This was a retrospective study on transfusion data from the 2013 calendar year. This study included a survey component that asked about hospital RBC selection and transfusion practices and a data collection component where participants submitted information on RBC unit disposition including blood group and D type of unit and recipient. Units administered to recipients of unknown ABO or D group were excluded. RESULTS: Thirty‐eight hospitals in 11 countries responded to the survey, 30 of which provided specific RBC unit disposition data. Overall, 11.1% (21, 235/191, 397) of group O units were transfused to non‐O recipients; 22.6% (8777/38, 911) of group O D– RBC units were transfused to O D+ recipients, and 43.2% (16, 800/38, 911) of group O D– RBC units were transfused to recipients that were not group O D–. Disposition of units and hospital transfusion policy varied within and across hospitals of different sizes, with transfusion of group O D– units to non‐group O D– patients ranging from 0% to 33%. CONCLUSION: A significant proportion of group O and D– RBC units were transfused to compatible, nonidentical recipients, although the frequency of this practice varied across sites.