Fast 3D magnetic resonance fingerprinting for a whole‐brain coverage. Issue 4 (22nd August 2017)

• Record Type: Journal Article
• Authors: Ma, Dan; Jiang, Yun; Chen, Yong; McGivney, Debra; Mehta, Bhairav; Gulani, Vikas; Griswold, Mark
• Is Part Of: Magnetic resonance in medicine. Volume 79:Issue 4(2018)
• Page Start: 2190
• Page End: 2197
• Publication Date: 2017-08-22
• Subjects: MR fingerprinting -- 3D -- T1; T2; relaxometry; Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.26886
• Languages: English
• ISSNs: 0740-3194

Abstract

Abstract : Purpose: The purpose of this study was to accelerate the acquisition and reconstruction time of 3D magnetic resonance fingerprinting scans. Methods: A 3D magnetic resonance fingerprinting scan was accelerated by using a single‐shot spiral trajectory with an undersampling factor of 48 in the x‐y plane, and an interleaved sampling pattern with an undersampling factor of 3 through plane. Further acceleration came from reducing the waiting time between neighboring partitions. The reconstruction time was accelerated by applying singular value decomposition compression in k‐space. Finally, a 3D premeasured B1 map was used to correct for the B1 inhomogeneity. Results: The T1 and T2 values of the International Society for Magnetic Resonance in Medicine/National Institute of Standards and Technology MRI phantom showed a good agreement with the standard values, with an average concordance correlation coefficient of 0.99, and coefficient of variation of 7% in the repeatability scans. The results from in vivo scans also showed high image quality in both transverse and coronal views. Conclusions: This study applied a fast acquisition scheme for a fully quantitative 3D magnetic resonance fingerprinting scan with a total acceleration factor of 144 as compared with the Nyquist rate, such that 3D T1, T2, and proton density maps can be acquired with whole‐brain coverage at clinical resolution in less than 5 min. Magn Reson Med 79:2190–2197, 2018. © 2017 International Society for Magnetic Resonance in Medicine.