A ligand and Palladium‐free Avenue for Cyanation of Aryl Halides: The Art of Samarium Powder in C–C Coupling Reaction. Issue 33 (30th August 2019)

• Record Type: Journal Article
• Authors: Moghaddam, Firouz Matloubi; Pourkaveh, Raheleh; Gholamtajari, Milad; Karimi, Ashkan
• Is Part Of: ChemistrySelect. Volume 4:Issue 33(2019)
• Page Start: 9618
• Page End: 9621
• Publication Date: 2019-08-30
• Subjects: Cyanation -- Ligand-free -- Palladium-free -- Sammarium powder -- Sodium cyanide; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201902018
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: This is the first study of samarium powder catalyzed cyanation reaction of aryl halides, bearing electron‐withdrawing and electron‐releasing substituents, in the presence of NaCN to afford corresponding benzonitriles in high yields. This protocol takes the advantage of being done in the absence of additive, ligand and precious transition metals such as palladium. Abstract : The first report of samarium powder catalyzed benzonitlile synthesis in the absence of any ligand and precious transition metals is described. The couplings performed in the DMSO provided the corresponding coupling products in good yields. The catalyst can be separated from the reaction mixture by simple filtration and reused easily for three successive runs without discernible decrease in its catalytic activity.