Bacteria‐Resistant Single Chain Cyclized/Knotted Polymer Coatings. (25th June 2019)

• Record Type: Journal Article
• Authors: Xu, Qian; A, Sigen; Venet, Manon; Gao, Yongsheng; Zhou, Dezhong; Wang, Wei; Zeng, Ming; Rotella, Chiara; Li, Xiaolin; Wang, Xi; Lyu, Jing; Rodriguez, Brian J.; Wang, Wenxin
• Is Part Of: Angewandte Chemie. Volume 131:Number 31(2019)
• Page Start: 10726
• Page End: 10730
• Publication Date: 2019-06-25
• Subjects: Antimikrobielle Oberflächen -- Beschichtungen -- Cyclisierte/verknotete Einzelkettenpolymere -- Multivinyl-Monomere -- RAFT-Polymerisation; Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201904818
• Languages: English
• ISSNs: 0044-8249

Abstract

Abstract: Further to conventional linear, branched, crosslinked, and dendritic polymers, single chain cyclized/knotted polymers (SCKPs) have emerged as a new class of polymer structure with unique properties. Herein, the development of bacteria‐resistant SCKPs is reported and the effect of this structure on the resistance of polymer materials to bacteria is investigated. Four SCKPs were synthesized by reversible addition fragmentation chain transfer (RAFT) homopolymerization of multivinyl monomers (MVMs) and then crosslinked by UV light to form SCKP films. Regardless of MVM type used, the resulting SCKP films showed much higher resistance to bacteria, and up to 75 % less bacterial attachment and biofilm formation, in comparison with the corresponding non‐SCKP films. This is due to the altered surface morphology and hydrophobicity of the SCKP films. These results highlight the critical role of the SCKP structure in enhancing the resistance of polymeric materials to bacteria. Abstract : Antibakteriell verknotet : Cyclisierte/verknotete Einzelkettenpolymerfilme (SCKP‐Filme), die mittels RAFT‐Homopolymerisation von Multivinyl‐Monomeren (MVMs) gefolgt von Vernetzung durch UV‐Licht synthetisiert wurden, zeigen aufgrund ihrer veränderten Oberflächenmorphologie eine höhere Resistenz gegenüber Bakterienanheftung und Biofilmbildung als Filme ohne SCKPs. Somit können sie zur Beschichtung medizinischer Geräte eingesetzt werden.