To Induce Immune Reconstitution Inflammatory Syndrome or Suppress It: The Spectrum of Mycobacterium genavense in the Antiretroviral Era. (18th June 2020)

• Record Type: Journal Article
• Authors: Manion, Maura; Lynn, Niamh; Pei, Luxin; Hammoud, Dima A; Laidlaw, Elizabeth; Roby, Gregg; Metzger, Dorinda; Mejia, Yolanda; Lisco, Andrea; Zelazny, Adrian; Holland, Steve; Vachon, Marie-Louise; Scherer, Matthew; Bergin, Colm; Sereti, Irini
• Is Part Of: Clinical infectious diseases. Volume 72:Number 2(2021)
• Page Start: 315
• Page End: 318
• Publication Date: 2020-06-18
• Subjects: Mycobacterium genavense -- IRIS -- HIV; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciaa753
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: Mycobacterium genavense is a challenging opportunistic pathogen to diagnose and manage in patients with human immunodeficiency virus (HIV). Persistent immunosuppression or protracted immune reconstitution inflammatory syndrome can lead to complicated clinical courses. We describe 3 cases of M. genavense in patients with HIV representing the spectrum between disease burden and strength of immune response.