Carcinoembryonic antigen-specific, fluorescent image-guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer. Issue 4 (21st January 2020)

• Record Type: Journal Article
• Authors: Schaap, D P; Valk, K S; Deken, M M; Meijer, R P J; Burggraaf, J; Vahrmeijer, A L; Kusters, M; Kusters, M; Boogerd, L S F; Schaap, D P; Voogt, E L K; Nieuwenhuijzen, G A P; Rutten, H J T; de Hingh, I H J T; Burger, J W A; Nienhuijs, S W; de Valk, K S; Meijer, R P J; Burggraaf, J; Brandt-Kerkhof, A R M; Verhoef, C; Madsen, E V E; van Kooten, J P; Framery, B; Gutowski, M; PM-hlegrin, A; Cailler, F; van Lijnschoten, I; Vahrmeijer, A L; Hoogstins, C E S; Boogerd, L S F; de Valk, K S; Deken, M M; Meijer, R P J;
• Is Part Of: British journal of surgery. Volume 107:Issue 4(2020)
• Page Start: 334
• Page End: 337
• Publication Date: 2020-01-21
• Subjects: Surgery -- Periodicals; 617.005
• DOI: 10.1002/bjs.11523
• Languages: English
• ISSNs: 0007-1323

Abstract

Graphical Abstract: This multicentre pilot study investigated the role of peroperative carcinoembryonic antigen (CEA)-specific fluorescence imaging during cytoreductive surgery–hyperthermic intraperitoneal chemotherapy surgery in peritoneal metastasized colorectal cancer. A correct change in peritoneal carcinomatosis index (PCI) owing to fluorescence imaging was seen in four of the 14 included patients. The use of SGM-101 in patients with peritoneally metastasized colorectal carcinoma is feasible, and allows intraoperative detection of tumour deposits and alteration of the PCI. Augmented reality guidance