Synthesis and catalytic activity of palladium complexes bearing N-heterocyclic carbenes (NHCs) and 1, 4, 7-triaza-9-phosphatricyclo[5.3.2.1]tridecane (CAP) ligands. Issue 27 (18th June 2021)

• Record Type: Journal Article
• Authors: Scattolin, Thomas; Voloshkin, Vladislav A.; Martynova, Ekaterina; Vanden Broeck, Sofie M. P.; Beliš, Marek; Cazin, Catherine S. J.; Nolan, Steven P.
• Is Part Of: Dalton transactions. Volume 50:Issue 27(2021)
• Page Start: 9491
• Page End: 9499
• Publication Date: 2021-06-18
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/d1dt01716k
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : Two synthetic approaches to cis -[Pd(CAP)(NHC)Cl2 ] are reported. The catalytic performance of these complexes in the Buchwald–Hartwig aryl amination reaction showed the complex bearing IPr to be the most efficient. Abstract : The synthesis and characterization of novel palladium complexes bearing N -heterocyclic carbenes (NHCs) and 1, 4, 7-triaza-9-phosphatricyclo[5.3.2.1]tridecane (CAP) are reported. These organometallic complexes can be easily obtained using two different synthetic strategies that involve either the substitution of the pyridine ligand from trans -[Pd(NHC)(Py)Cl2 ] or by simple addition of the CAP ligand to dimeric species [Pd(NHC)Cl2 ]2 . The mixed NHC/CAP complexes were tested as pre-catalysts in the Buchwald–Hartwig aryl amination coupling, showing good catalytic activity, especially in the case of cis -[Pd(IPr)(CAP)Cl2 ].