Description of a Sulfitobacter Strain and Its Extracellular Cyclodipeptides. (19th September 2011)

• Record Type: Journal Article
• Authors: Long, Cong; Lu, Xiao-Ling; Gao, Yun; Jiao, Bing-Hua; Liu, Xiao-Yu
• Is Part Of: Evidence-based complementary and alternative medicine. Volume 2011(2011)
• Publication Date: 2011-09-19
• Subjects: Alternative medicine -- Periodicals; 615.505
• DOI: 10.1155/2011/393752
• Languages: English
• ISSNs: 1741-427X

Abstract

Abstract : A marine bacterium M44 was separated from 30 m deep seawater in the East China Sea (26 ° 28.3 ′ N 122 ° 29.0 ′ E) in 2006. 16S rDNA gene sequence comparison showed that the strain M44 was a member of the genus Sulfitobacter and highly similar to KMM 3554 T . A series of experiments demonstrated that this strain M44 had many distinctive characteristics: its cells were gram-negative and mesophilic; its colonies were slightly yellowish, round, convex, and smooth; and it could grow at 10–28 ° C, pH 6.0–10.0, and in the presence of 0–12.5% (w/v) NaCl; the optimum growth conditions were 25 ° C and pH 7.0, and the optimum Na + concentration was 2.5%. In addition, strain M44 contained 18 : 1 ω7c, 11 methyl 18 : 1 ω7c and 16 : 0 fatty acids as major fatty acids, and the genomic DNA G+C content was 58.04 mol%. According to our results of the secondary metabolites, six cyclodipeptides were isolated from the strain M44, which were Cyclo (Val-Leu), Cyclo (Phe-Val), Cyclo (Phe-Leu), Cyclo (Leu-Ile), Cyclo (Phe-Ile), and Cyclo (Trp-Pro). It is the first study of secondary metabolites isolated from this genus.