Front Cover: Manufacture of Multilayered Artificial Cell Membranes through Sequential Bilayer Deposition on Emulsion Templates (ChemBioChem 13/2021). (10th June 2021)

• Record Type: Journal Article
• Authors: Ip, Tsoi; Li, Qien; Brooks, Nick; Elani, Yuval
• Is Part Of: Chembiochem. Volume 22:Number 13(2021)
• Page Start: 2182
• Page End: 2182
• Publication Date: 2021-06-10
• Subjects: artificial cells -- droplet technologies -- membrane biophysics -- molecular bioengineering -- vesicles; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1002/cbic.202100224
• Languages: English
• ISSNs: 1439-4227

Abstract

Abstract : We have developed a technology to manufacture multilayered lipid vesicles . Individual bilayers are deposited layer‐by‐layer, allowing us to regulate the number of bilayers and their individual composition. This depiction of our structures portrays the self‐assembly underpinning our method (bottom left) and our discovery that phase‐separated domains align with one another through the layers (yellow). The undulating membranes represent the fluctuation analysis technique that we use to show that the mechanical properties of the vesicle scale with the number of layers. More information can be found in the Full Paper by Y. Elani et al. Image by Zehua Hu.