Scattering Coefficients of Mice Organs Categorized Pathologically by Spectral Domain Optical Coherence Tomography. (13th April 2014)

• Record Type: Journal Article
• Authors: Zhang, Q. Q.; Wu, X. J.; Wang, C.; Zhu, S. W.; Wang, Y. L.; Gao, Bruce Z.; Yuan, X.-C.
• Other Names: Zhang Shiwu Academic Editor.
• Is Part Of: BioMed research international. Volume 2014(2014)
• Publication Date: 2014-04-13
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2014/471082
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Differences in tissue density cause a variety of scattering coefficients. To quantify optical coherence tomography (OCT) images for diagnosis, the tissue's scattering coefficient is estimated by curve fitting the OCT signals to a confocal single backscattering mode. The results from a group of 30 mice show that the scattering coefficients of bone, skin, liver, brain, testis, and spleen can be categorized into three groups: a scattering coefficient between 1.947 and 2.134 mm −1 : bone and skin; a scattering coefficient between 1.303 and 1.461 mm −1 : liver and brain; a scattering coefficient between 0.523 and 0.634 mm −1 : testis and spleen. The results indicate that the scattering coefficient is tissue specific and could be used in tissue diagnosis.