Molecular Mechanism Underlying Lymphatic Metastasis in Pancreatic Cancer. (22nd January 2014)
- Record Type:
- Journal Article
- Title:
- Molecular Mechanism Underlying Lymphatic Metastasis in Pancreatic Cancer. (22nd January 2014)
- Main Title:
- Molecular Mechanism Underlying Lymphatic Metastasis in Pancreatic Cancer
- Authors:
- Xiao, Zhiwen
Luo, Guopei
Liu, Chen
Wu, Chuntao
Liu, Liang
Liu, Zuqiang
Ni, Quanxing
Long, Jiang
Yu, Xianjun - Other Names:
- Takao Sonshin Academic Editor.
- Abstract:
- Abstract : As the most challenging human malignancies, pancreatic cancer is characterized by its insidious symptoms, low rate of surgical resection, high risk of local invasion, metastasis and recurrence, and overall dismal prognosis. Lymphatic metastasis, above all, is recognized as an early adverse event in progression of pancreatic cancer and has been described to be an independent poor prognostic factor. It should be noted that the occurrence of lymphatic metastasis is not a casual or stochastic but an ineluctable and designed event. Increasing evidences suggest that metastasis-initiating cells (MICs) and the microenvironments may act as a double-reed style in this crime. However, the exact mechanisms on how they function synergistically for this dismal clinical course remain largely elusive. Therefore, a better understanding of its molecular and cellular mechanisms involved in pancreatic lymphatic metastasis is urgently required. In this review, we will summarize the latest advances on lymphatic metastasis in pancreatic cancer.
- Is Part Of:
- BioMed research international. Volume 2014(2014)
- Journal:
- BioMed research international
- Issue:
- Volume 2014(2014)
- Issue Display:
- Volume 2014, Issue 2014 (2014)
- Year:
- 2014
- Volume:
- 2014
- Issue:
- 2014
- Issue Sort Value:
- 2014-2014-2014-0000
- Page Start:
- Page End:
- Publication Date:
- 2014-01-22
- Subjects:
- Medicine -- Periodicals
Biology -- Periodicals
Biotechnology -- Periodicals
Life sciences -- Periodicals
610.5 - Journal URLs:
- https://www.hindawi.com/journals/bmri/ ↗
- DOI:
- 10.1155/2014/925845 ↗
- Languages:
- English
- ISSNs:
- 2314-6133
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 17439.xml