Effects of Anti-TNF Alpha Drugs on Disability in Patients with Rheumatoid Arthritis: Long-Term Real-Life Data from the Lorhen Registry. (6th July 2014)

• Record Type: Journal Article
• Authors: Filippini, Matteo; Bazzani, Chiara; Atzeni, Fabiola; Sarzi Puttini, Piercarlo; Marchesoni, Antonio; Favalli, Ennio Giulio; Caporali, Roberto; Cavagna, Lorenzo; Gorla, Roberto
• Other Names: Saketkoo Lesley-Ann Academic Editor.
• Is Part Of: BioMed research international. Volume 2014(2014)
• Publication Date: 2014-07-06
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2014/416892
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : This study involving 1033 patients with RA confirms the effectiveness of etanercept, adalimumab, and infliximab in reducing RA-related disability even in patients with a history of highly active and longstanding RA. Moreover, we found that the improvement in disability was biphasic, with a marked improvement during the first year of anti-TNF therapy, followed by slower but significant recovery over the subsequent four years.