Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo Cardiomyopathy. (3rd December 2012)

• Record Type: Journal Article
• Authors: Murakami, Masanori; Matsushita, Noriko; Arai, Rie; Takahashi, Naohiro; Kawamura, Ryuki; Suzuki, Sayaka; Takekawa, Sachio; Iwashima, Fumiko; Shibui, Takashi; Hata, Akihiro; Ogawa, Yoshihiro; Horiuchi, Toshiyuki
• Other Names: Kita T. Academic Editor.; Moore W. V. Academic Editor.; Moriwaki Y. Academic Editor.
• Is Part Of: Case reports in endocrinology. Volume 2012(2012)
• Publication Date: 2012-12-03
• Subjects: Endocrinology -- Periodicals; Endocrinology -- Case studies -- Periodicals; Endocrine glands -- Diseases -- Periodicals; Endocrinology; Endocrine System Diseases; Endocrine glands -- Diseases; Endocrinology; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.4
• DOI: 10.1155/2012/580481
• Languages: English
• ISSNs: 2090-6501

Abstract

Abstract : We report a 65-year-old woman with isolated adrenocorticotropic hormone (ACTH) deficiency. The patient was transported to the emergency outpatient department by ambulance complaining of malaise and nausea. Because her laboratory data revealed hyponatremia, we performed endocrinological examinations and diagnosed isolated ACTH deficiency. After admission, she went into a delirious state and suffered from takotsubo cardiomyopathy due to adrenal insufficiency. Replacement therapy with hydrocortisone sufficiently improved her delirium and cardiomyopathy. We conclude that her unstable mental state and myocardial dysfunction were closely related to adrenal insufficiency and suggest that adrenal crisis may cause delirium and Takotsubo cardiomyopathy.