Principles and open questions in functional brain network reconstruction. Issue 11 (20th May 2021)

• Record Type: Journal Article
• Authors: Korhonen, Onerva; Zanin, Massimiliano; Papo, David
• Is Part Of: Human brain mapping. Volume 42:Issue 11(2021)
• Page Start: 3680
• Page End: 3711
• Publication Date: 2021-05-20
• Subjects: brain dynamics -- brain topology -- edges -- functional imaging -- functional networks -- nodes -- resting state -- structure–function relationship -- temporal networks; Brain mapping -- Periodicals; 611.81
• DOI: 10.1002/hbm.25462
• Languages: English
• ISSNs: 1065-9471

Abstract

Abstract: Graph theory is now becoming a standard tool in system‐level neuroscience. However, endowing observed brain anatomy and dynamics with a complex network representation involves often covert theoretical assumptions and methodological choices which affect the way networks are reconstructed from experimental data, and ultimately the resulting network properties and their interpretation. Here, we review some fundamental conceptual underpinnings and technical issues associated with brain network reconstruction, and discuss how their mutual influence concurs in clarifying the organization of brain function. Abstract : Graph theory is now becoming a standard tool in system‐level neuroscience. However, endowing observed brain anatomy and dynamics with a complex network representation involves often covert theoretical assumptions and methodological choices which affect the way networks are reconstructed from experimental data, and ultimately the resulting network properties and their interpretation. Here, we review some fundamental conceptual underpinnings and technical issues associated with brain network reconstruction, and discuss how their mutual influence concurs in clarifying the organization of brain function. ​