Recent developments in the synthesis of N-aryl sulfonamides. Issue 15 (3rd August 2021)

• Record Type: Journal Article
• Authors: Wu, Huizhen; Chen, Xuesong; Sun, Nabo; Sanchez-Mendoza, Alberto
• Is Part Of: Synthetic communications. Volume 51:Issue 15(2021)
• Page Start: 2287
• Page End: 2304
• Publication Date: 2021-08-03
• Subjects: Biological activities -- laboratory synthesis -- N-arylsulfonamides -- organic synthesis -- pharmaceutical chemistry; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2021.1936060
• Languages: English
• ISSNs: 0039-7911

Abstract

Abstract: The construction of N-aryl sulfonamides is usually an important reaction in organic synthesis because these compounds are privileged in the structure of many natural products and pharmaceutical molecules. Also, N-aryl sulfonamides are well-known due to their antibacterial, antitumor, and anti-HIV biological activities. Therefore, research on the laboratory synthesis of N-aryl sulfonamides is an important challenge in organic synthesis. In this review, we discussed on methods reported up to now for the synthesis of N-aryl sulfonamides with the goal of stimulating further progresses in this field. We believe that this review will open up a new road for the preparation of pharmaceutically and biologically active sulfonamides. Graphical Abstract: UF0001