Triterpene-farnesyl hydroquinone conjugates from Ganoderma calidophilum. Issue 13 (15th June 2021)

• Record Type: Journal Article
• Authors: Zhang, Lan-Jun; Xie, Yong; Wang, Ya-Qin; Xu, Yan-Yong; Mei, Ren-Qiang
• Is Part Of: Natural product research. Volume 35:Issue 13(2021)
• Page Start: 2199
• Page End: 2204
• Publication Date: 2021-06-15
• Subjects: Ganoderma calidophilum -- ganocalidoin A -- ganocalidoin B; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1667346
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new lanostane-type triterpenoids characterized with farnesyl hydroquinone moieties, ganocalidoins A (1 ) and B (2 ), were isolated from the fruiting body of Ganoderma calidophilum, together with two known tripterpenes (3 -4 ). The structures of compounds 1 and 2 were determined by extensive spectroscopic data including HRESIMS, 1D and 2D NMR. Ganocalidoins A and B showed anti-oxidant capacity with IC50 values of 38.7 ± 2.8 and 34.2 ± 1.8 μM, respectively. The compounds did not show tyrosinase inhibition activity. Graphical Abstract: UF0001