N-Doped carbon as a solid base catalyst for continuous flow Knoevenagel condensation. Issue 7 (6th May 2021)

• Record Type: Journal Article
• Authors: Brzęczek-Szafran, Alina; Gwóźdź, Magdalena; Kolanowska, Anna; Krzywiecki, Maciej; Latos, Piotr; Chrobok, Anna
• Is Part Of: Reaction chemistry & engineering. Volume 6:Issue 7(2021)
• Page Start: 1246
• Page End: 1253
• Publication Date: 2021-05-06
• Subjects: Reaction mechanisms (Chemistry) -- Periodicals; Chemical engineering -- Periodicals; Chemical engineering; Reaction mechanisms (Chemistry); Periodicals; 547.705
• DOI: 10.1039/d1re00016k
• Languages: English
• ISSNs: 2058-9883

Abstract

Abstract : A stability survey of a basic N-doped carbon catalyst in a continuous flow process together with a study of process parameters affecting the batch system and their correlation to the flow protocol is described. Abstract : The application of N-doped carbon as a basic, heterogeneous catalyst in a continuous-flow process is described for the first time. The Knoevenagel condensation reaction was chosen to demonstrate the potential of N-doped carbon toward the development of sustainable, scalable processes that require a basic catalyst. The practical potential and performance advantages of the flow approach compared to a conventional batch system were envisioned. Under flow conditions, products were continuously synthesized for 200 h with high conversions up to 95%. The presented metal-free flow system successfully operated under mild reaction conditions, with temperatures ranging from 25 to 70 °C and ethanol as a solvent, which embody key principles of green chemistry.