Development of a novel radiotheranostic platform with a DOTA-based trifunctional chelating agent. Issue 52 (7th June 2021)
- Record Type:
- Journal Article
- Title:
- Development of a novel radiotheranostic platform with a DOTA-based trifunctional chelating agent. Issue 52 (7th June 2021)
- Main Title:
- Development of a novel radiotheranostic platform with a DOTA-based trifunctional chelating agent
- Authors:
- Nakashima, Kazuma
Iikuni, Shimpei
Watanabe, Hiroyuki
Ono, Masahiro - Abstract:
- Abstract : We designed and synthesized a novel DOTA-based trifunctional agent containing a click ligation moiety and a pharmacological modifier for the development of a radiotheranostic platform. Abstract : Radiotheranostics has attracted attention as a powerful strategy for treating cancer patients with precision medicine. We designed and synthesized a novel DOTA-based trifunctional agent, ADIBO-DOTADG-ALB (ADA), which allowed compounds with targeting ligands, radiometals, and an albumin binder to be readily prepared. ADA exhibited promising properties as a theranostic platform.
- Is Part Of:
- Chemical communications. Volume 57:Issue 52(2021)
- Journal:
- Chemical communications
- Issue:
- Volume 57:Issue 52(2021)
- Issue Display:
- Volume 57, Issue 52 (2021)
- Year:
- 2021
- Volume:
- 57
- Issue:
- 52
- Issue Sort Value:
- 2021-0057-0052-0000
- Page Start:
- 6432
- Page End:
- 6435
- Publication Date:
- 2021-06-07
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d1cc00823d ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 17421.xml